Evaluation of a drug study (graduate nurse practitioner

Evaluation of a drug study (graduate nurse practitioner

Order Description

Please find a drug study (mental health related preferred)on Methylcolbalamin (B12) and address the following questions

Research – Community Drug Study
.

Review a drug study on a complimentary medicine using the format below [copy and paste onto your document] answering all the questions thoroughly.

Evaluating Research

Ethical: safety of pt, consent obtained

Statement of Objectives: goals clearly defined

Experimental methods: appropriate to study goals, accuracy and reliability of the methods

Statistical methods: How were patients selected, were there enough patients, do the patients represent the population who will be using the drug, long term study how

many lost to follow up & how was this accounted for, placebo, how were patients assigned to groups, were patients receiving other therapies during the trial & how was

this accounted for, appropriate statistical tests. Patients that dropped out what was the reason?

Conclusions: Data if sound justify conclusions, does the drug offer significant advantages of cost, efficacy, safety over existing agents? Was the objective reached or

did it change in the conclusion? What are your conclusions of this study weaknesses, strengths etc. Statistical values p, CI etc……

P value is significant when it less than 1 in 20 or expressed as P<0.05. This means that if the study was repeated 20 times at least 19 out of 20 would yield

conclusions similar to those observed by the researchers. Any difference no matter how small may be found to be statistically significant if the sample size is large

enough. A STATISTICALLY SIGNIFICANT RESULT, HOWEVER MAY NOT BE CLINICALLY SIGNIFICANT. An outcome is said to be clinically significant if it makes enough difference to

both patients and providers to change current practice.

Research – Community Drug Study
.

Review a drug study on a complimentary medicine using the format below [copy and paste onto your document] answering all the questions thoroughly.

Evaluating Research

Ethical: safety of pt, consent obtained

Statement of Objectives: goals clearly defined

Experimental methods: appropriate to study goals, accuracy and reliability of the methods

Statistical methods: How were patients selected, were there enough patients, do the patients represent the population who will be using the drug, long term study how

many lost to follow up & how was this accounted for, placebo, how were patients assigned to groups, were patients receiving other therapies during the trial & how was

this accounted for, appropriate statistical tests. Patients that dropped out what was the reason?

Conclusions: Data if sound justify conclusions, does the drug offer significant advantages of cost, efficacy, safety over existing agents? Was the objective reached or

did it change in the conclusion? What are your conclusions of this study weaknesses, strengths etc. Statistical values p, CI etc……

P value is significant when it less than 1 in 20 or expressed as P<0.05. This means that if the study was repeated 20 times at least 19 out of 20 would yield

conclusions similar to those observed by the researchers. Any difference no matter how small may be found to be statistically significant if the sample size is large

enough. A STATISTICALLY SIGNIFICANT RESULT, HOWEVER MAY NOT BE CLINICALLY SIGNIFICANT. An outcome is said to be clinically significant if it makes enough difference to

both patients and providers to change current practice.

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